When a patient decides to start using Malegra, undoubtedly it is necessary to learn some information about the chosen medicine for reaching the best result. Malegra presents a special medication which combines the erectile dysfunction-treating power of sildenafil citrate with Fluoxetine, an antidepressant used to treat premature ejaculation. Its active ingredients are sildenafil citrate and tramadol hydrochloride.

Basically, after taking Malegra pill a patient gets the effect of two pills: one that will enhance and prolong erection and the other that will prevent you from getting too aroused and ending the gaiety just when they’re getting started. This fantastic mixture makes a patient last longer, lets you experience the ultimate pleasure and ensures that you will be a great lover and fully satisfy your partner, enjoying wonderful sexual life!

Clinical tests have proved Malegra to be of exceptional efficiency and of excellent quality in treating erectile dysfunction, premature ejaculation, and even, to a slight degree, depression. As fluoxetine is approved for treatment of depression it is also used to prevent premature ejaculation. 

Today Malegra has become one of the most popular medications of its kind on the market; it belongs to one of the leading brands in the new generation of sexual enhancement medications combining PDE-5 inhibitors and short-acting antidepressants like fluoxetine. 

It is well known that as a rule penile erection during sexual intercourse is caused by increased blood flow resulting from the relaxation of penile arteries and the smooth muscle of the corpus cavernosum. This reaction is mediated by the release of nitric oxide from nerve and endothelial cells stimulating the synthesis of cGMP (cyclic guanosine monophosphate) in smooth muscle cells. This cGMP relaxes smooth muscle and increases blood flow to the genitals.

The bringing down of inhibitor (substance decelerating biological processes and chemical reactions) called “phosphodiesterase type 5 (PDE-5)” enhances erectile function by increasing the amount of cGMP in the penis. Thus, tadalafil, the main ingredient of Malegra, inhibits this PDE-5 enzyme; anyway, this will have no effect without direct sexual stimulation of the penis. 

However, patients should note that for achieving the best results they are strongly advised to consult a physician to determine a safe and effective dosage of Malegra after defining the general health condition.

Physicians persuade Malegra belongs to the strongest, the most efficient combined erectile dysfunction remedies in the market, providing you a perfect mood and keeping the effect for a long time. 

Remember, that you mustn’t take Malegra if you are taking simultaneously any medications containing nitrates such as nitroglycerin or isosorbide mononitrate; of course if you have some doubts or questions, consult your physician to avoid unpleasant unexpectedness.